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biovision.K777-100 Creatine Kinase (CK) Activity Colorimetric Assay Kit 100次/盒
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货品编号: biovision.K777-100
品牌: biovision
品名: Creatine Kinase (CK) Activity Colorimetric Assay Kit
规格: 100次/盒
产品描述:
Creatine Kinase (CK) also known as creatine phosphokinase (CPK) and ATP: creatine
N-phosphotransferase is a common cellular enzyme (EC 2.7.3.2). It catalyzes the reversible
conversion of creatine and ATP into ADP and phosphocreatine. CK is widely expressed
in various tissues and cell types, with highest activity in striated muscles, heart tissue and
brain. CK consists of two subunits: M (muscle) and B (brain), and has three isoenzymes:
CK-MM (skeleton muscle), CK-MB (cardiac muscle), and CK-BB (brain). Increased CK
level is associated with many diseases such as myocardial infarction, muscular dystrophy,
pulmonary infarction and brain tumors. Accurate measurement of CK is crucial for early
diagnosis, prediction and therapeutic strategy. In BioVision’s Creatine Kinase Activity
Colorimetric Assay kit, creatine kinase converts creatine into phosphocreatine and ADP.
The generated phoshocreatine and ADP reacts with CK Enzyme Mix to form an intermediate
, which reduces a colorless Probe to a colored product with strong absorbance at 450 nm.
The CK Activity Assay is high-throughput adaptable, simple and sensitive. This assay kit can
detect Creatine Kinase activity less than 1 mU.
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