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bioss.bs-20594R Rabbit Anti-TLR4 antibody 50ul
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产品描述: The Toll-like receptor 4 by activating natural immunity, specific immune response involved in the start-up, Toll-like
receptor 4 as an important signal transduction transmembrane receptor involved in the toxin-induced inflammation
in the pathological process, its mechanisms of control On a growing concern. all regions were either double-stranded
or sequenced with an alternatechemistry or covered by high quality data(i.e., phred quality >=30); an attempt was
made to resolve all sequencing problems, such as compressions and repeats; all regions were covered by at least
one subclone; and the assembly was confirmed by restriction digest, except on the rare occasion of the clone being a
YAC. The following abbreviations are used to associate primary accession numbers given in the feature table with their
source databases: Em:, EMBL; Sw:, SWISSPROT; Tr:, TREMBL; Wp:, WORMPEP; Information on the WORMPEP
database can be found at. TLR-4 plays an important role in microvascular leakage and leukocyte adhesion under the
inflammatory condition associated with nonseptic thermal injury.
Function: Cooperates with LY96 and CD14 to mediate the innate immune response to bacterial lipopolysaccharide (LPS). Acts via
MYD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Also
involved in LPS-independent inflammatory responses triggered by Ni(2+). These responses require non-conserved
histidines and are, therefore, species-specific.
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