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AAT Bioquest.AAT-20508 Cal-590-Dextran Conjugate *MW 3,000* 1mg/瓶
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产品描述: Calcium measurement is critical for numerous biological investigations. Fluorescent probes that show spectral responses
upon binding calcium have enabled researchers to investigate changes in intracellular free calcium concentrations by using
fluorescence microscopy, flow cytometry, fluorescence spectroscopy and fluorescence microplate readers. Cells may be
physically loaded with the cell-impermeant salt forms of these dextran-conjugated calcium indicators using patch pipette or
microinjection. The fluorescence signal from these cells is measured using fluorescence microscopy. The dextran forms of
our calcium indicators show a dramatic reduction in both leakage and compartmentalization compared to the AM ester forms.
Among the fluorescent calcium indicator dextran conjugates, Cal-590 dextran conjugates might be a better choice than other
red fluorescent dextrtan conjugates due to its higher fluorescence quantum yield and larger fluorescence enhancement by
calcium.
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