BIOXCELL.BE0189-1mg anti-human CD40

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货品编号：BIOXCELL.BE0189-1mg

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品牌：bioxcell
所属分类：细胞分离

货品编号：  BIOXCELL.BE0189-1mg          品牌：  <span style="display: inline !important; float: none; background-color: transparent; color: rgb(0, 0, 0); cursor: text; font-family: Arial,Verdana,sans-serif; font-size: 12px; font-style: normal; font-variant: normal; font-weight: 400; letter-spacing: normal; orphans: 2; text-align: left; text-decoration: none; text-indent: 0px; text-transform: none; -webkit-text-stroke-width: 0px; white-space: normal; word-spacing: 0px;">BIOXCELL      品名：  <span style="display: inline !important; float: none; background-color: transparent; color: rgb(0, 0, 0); cursor: text; font-family: Arial,Verdana,sans-serif; font-size: 12px; font-style: normal; font-variant: normal; font-weight: 400; letter-spacing: normal; orphans: 2; text-align: left; text-decoration: none; text-indent: 0px; text-transform: none; -webkit-text-stroke-width: 0px; white-space: normal; word-spacing: 0px;">anti-human CD40      规格：  <span style="display: inline !important; float: none; background-color: transparent; color: rgb(0, 0, 0); cursor: text; font-family: Arial,Verdana,sans-serif; font-size: 12px; font-style: normal; font-variant: normal; font-weight: 400; letter-spacing: normal; orphans: 2; text-align: left; text-decoration: none; text-indent: 0px; text-transform: none; -webkit-text-stroke-width: 0px; white-space: normal; word-spacing: 0px;">1mg    <strike></strike>      产品描述：     The G28.5 monoclonal antibody reacts with human CD40 also known as Bp50. CD40 is a 48 kDa type I transmembrane      glycoprotein that belongs to the tumor necrosis factor receptor (TNFR) superfamily. CD40 is expressed broadly on      antigen-presenting cells (APCs) such as dendritic cells, B cells, macrophages, and monocytes as well as non-immune      endothelial cells, basal epithelial cells, and a range of tumors. Upon binding to its ligand CD154, CD40 acts as a costimulatory      molecule for the activation of B cells, dendritic cells, monocytes, and other APCs. CD40 plays roles in B cell activation,      differentiation, proliferation and Ig isotype switching as well as dendritic cell maturation. Agonistic CD40 monoclonal antibodies      have been shown to activate APCs and promote anti-tumor T cell responses. The G28.5 antibody is an agonistic antibody that     has been shown to activate CD40 expressing APCs.

BIOXCELL.BE0189-1mg anti-human CD40

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